Description

Bicyclo[2.2.1]Heptane-1,4-Diyldimethanol is a specialized, high-purity diol derivative of norbornane, serving as a critical chiral building block and rigid spacer in advanced organic synthesis. Its unique bicyclic structure provides exceptional stereochemical control and molecular rigidity, making it invaluable for creating complex architectures with defined three-dimensional shapes. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular scaffolds for drug discovery, ligand design, and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key chiral precursor for synthesizing active pharmaceutical ingredients (APIs), particularly in neurology and oncology, where its rigid structure influences bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the norbornane core contributes to stability and target specificity.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing high-performance, thermally stable polymers, resins, and liquid crystals.
• Asymmetric Catalysis: Employed in the design and synthesis of chiral ligands and organocatalysts for stereoselective reactions.
• Advanced Research & Development: Serves as a versatile scaffold in medicinal chemistry for probing structure-activity relationships (SAR) and fragment-based drug discovery.
• Specialty Chemicals: Utilized in the formulation of adhesives, coatings, and electronic materials requiring enhanced mechanical and chemical resistance.

Basic Information

Item	Detail
Product Name	Bicyclo[2.2.1]Heptane-1,4-Diyldimethanol
CAS No.	1185307-52-1
Molecular Formula	C11H18O2
Molecular Weight	182.26 g/mol
Synonyms	1,4-Bis(hydroxymethyl)bicyclo[2.2.1]heptane; 1,4-Bis(hydroxymethyl)norbornane; Norbornane-1,4-dimethanol; 1,4-Norbornanedimethanol; Bicyclo[2.2.1]heptane-1,4-dimethanol; 1,4-Di(hydroxymethyl)bicyclo[2.2.1]heptane; (1R,4S)-Bicyclo[2.2.1]heptane-1,4-dimethanol (for specific stereoisomers); Contact for details on specific isomer availability.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-1,4-Diyldimethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) upon request, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.