Description

2-Bromo-4-(iso-Propyl-D7)-Pyridine is a deuterated pyridine derivative, specifically labeled with seven deuterium atoms on the isopropyl group. This compound is a critical building block in pharmaceutical research and development, enabling the creation of isotopically labeled drug candidates and metabolites for advanced pharmacokinetic and metabolic studies. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and analytical chemistry industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of deuterated active pharmaceutical ingredients (APIs) to study drug metabolism and improve pharmacokinetic profiles.
• Metabolite Synthesis: Used in the preparation of stable isotope-labeled internal standards for accurate LC-MS and GC-MS quantification in bioanalytical assays.
• Mechanistic Studies: Employed in reaction mechanism elucidation and isotope effect studies due to the deuterium labeling.
• Agrochemical Research: Serves as a precursor for developing novel, labeled agrochemicals and studying their environmental fate.
• Material Science: Potential building block for advanced organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Bromo-4-(iso-Propyl-D7)-Pyridine
CAS No.	1185306-04-0
Molecular Formula	C8D7BrN
Molecular Weight	202.10 g/mol
Synonyms	2-Bromo-4-(1-methylethyl-d7)pyridine; 2-Bromo-4-(propan-2-yl-d7)pyridine; 2-Bromo-4-isopropyl-d7-pyridine; 4-Isopropyl-d7-2-bromopyridine; (2-Bromo-4-pyridinyl)(1-methylethyl-d7); Deuterated 2-Bromo-4-isopropylpyridine; 2-Bromo-4-(iso-Propyl-D7)Pyridine; 2-Br-4-(i-Pr-d7)-Py
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(iso-Propyl-D7)-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ²H), HPLC, and GC-MS, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (²H NMR / MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.