Description

[5-(3,4-Dihydroisoquinolin-2(1H)-Ylcarbonyl)-1,2,4-Oxadiazol-3-Yl]Methylamine Hydrochloride is a high-purity, non-natural amino acid derivative and heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials. The CAS number for this compound is 1185302-44-6.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique fused isoquinoline-oxadiazole scaffold.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Synthesis: Acts as a precursor for developing new pesticides and herbicides with novel modes of action.
• Peptidomimetics: The amine functionality and heterocyclic core make it valuable for creating peptide mimics with enhanced stability and bioavailability.
• Ligand Synthesis for Catalysis: Used to prepare specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	[5-(3,4-Dihydroisoquinolin-2(1H)-Ylcarbonyl)-1,2,4-Oxadiazol-3-Yl]Methylamine Hydrochloride
CAS No.	1185302-44-6
Molecular Formula	C₁₄H₁₅ClN₄O₂
Molecular Weight	306.75 g/mol
Synonyms	1,2,4-Oxadiazole-3-methylamine, 5-[(1,2,3,4-tetrahydro-2-isoquinolinyl)carbonyl]-, hydrochloride; 5-(1,2,3,4-Tetrahydroisoquinoline-2-carbonyl)-1,2,4-oxadiazol-3-ylmethanamine hydrochloride; (5-((3,4-Dihydroisoquinoline-2(1H)-yl)carbonyl)-1,2,4-oxadiazol-3-yl)methanamine HCl; 1185302-44-6; UNII-9F6K3Y5J8I; CHEMBL3186661
EINECS	Contact for details

Quality Control

Our [5-(3,4-Dihydroisoquinolin-2(1H)-Ylcarbonyl)-1,2,4-Oxadiazol-3-Yl]Methylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under dry, inert conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.