Description

1-(Piperidin-3-Ylcarbonyl)Indoline, Sulfate is a high-purity, non-natural amino acid derivative and a key synthetic intermediate in modern pharmaceutical research. Its value lies in its complex heterocyclic structure, which serves as a privileged scaffold for constructing novel bioactive molecules. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly for the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-up: Serves as a key intermediate in the development of scalable synthetic routes for candidate drugs during pre-clinical and clinical stages.
• Chemical Biology Probes: Utilized in the synthesis of specialized molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and advanced intermediates.

Basic Information

Product Name	1-(Piperidin-3-Ylcarbonyl)Indoline, Sulfate
CAS No.	1185298-95-6
Molecular Formula	C14H18N2O • H2SO4
Molecular Weight	342.38 g/mol (for sulfate salt)
Synonyms	1-(3-Piperidylcarbonyl)indoline sulfate; Indoline-1-carboxylic acid, 3-piperidinyl ester, sulfate; 1-(Piperidine-3-carbonyl)indoline sulfate; 1-(3-Piperidinecarbonyl)indoline hydrogen sulfate; 1185298-95-6 (CAS); 1-(Piperidin-3-ylcarbonyl)indoline sulphate
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-3-Ylcarbonyl)Indoline, Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.