Description

(E/Z)-2-[2-(Cyclohexyl-D11)-2-(4-Hydroxycyclohexyl)]Vinylpyridine (Mixture Of Diastereomers) is a deuterated organic compound of significant interest in advanced chemical research and development. Its core value lies in its utility as a specialized building block or analytical standard for metabolic and pharmacokinetic studies, leveraging the deuterium labeling for precise tracking. This product is primarily needed by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions engaged in drug discovery and development.

Application

• Pharmaceutical Research: As a deuterium-labeled intermediate in the synthesis of novel drug candidates for improved metabolic stability (deuterium kinetic isotope effect).
• Metabolite Identification: Serving as a stable isotope-labeled internal standard in LC-MS and GC-MS analysis for accurate quantification of parent compounds and their metabolites.
• Mechanistic Studies: Used in probing reaction mechanisms and biological pathways where hydrogen/deuterium exchange is relevant.
• Chemical Synthesis: As a specialized synthon for constructing complex molecules containing a vinylpyridine moiety and a deuterated cyclohexyl group for structure-activity relationship (SAR) studies.
• Analytical Standard: Providing a high-purity reference material for method development and validation in analytical laboratories.

Basic Information

Product Name	(E/Z)-2-[2-(Cyclohexyl-D11)-2-(4-Hydroxycyclohexyl)]Vinylpyridine (Mixture Of Diastereomers)
CAS No.	1185245-16-2
Molecular Formula	C19H16D11NO
Molecular Weight	~299.5 g/mol
Synonyms	2-[2-(Cyclohexyl-d11)-2-(4-hydroxycyclohexyl)vinyl]pyridine; 2-[(E/Z)-2-(Cyclohexyl-d11)-2-(4-hydroxycyclohexyl)vinyl]pyridine; Deuterated Vinylpyridine Derivative; (E/Z)-2-[2-(Cyclohexyl-d11)-2-(4-Hydroxycyclohexyl)]Ethenylpyridine; 1185245-16-2; (E/Z)-2-[2-(Cyclohexyl-D11)-2-(4-Hydroxycyclohexyl)]Ethenylpyridine; (E/Z)-2-[2-(Cyclohexyl-D11)-2-(4-Hydroxycyclohexyl)]Ethenylpyridine (Mixture Of Diastereomers)
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and handled under strict quality protocols to ensure batch-to-batch consistency and isotopic purity. Each lot undergoes comprehensive analysis, including NMR (¹H, ²H, ¹³C) and HPLC/MS, to confirm chemical structure, deuterium incorporation, and diastereomeric ratio. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Total of diastereomers)
Deuterium Incorporation (²H NMR)	≥ 98 atom % D
Diastereomeric Ratio (HPLC)	Specified on COA
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.