Description

Lanoconazole-D3 is a deuterated isotopologue of the antifungal agent lanoconazole, specifically labeled with three deuterium atoms. This compound is a critical reference standard and labeled internal standard used in quantitative analytical methods, ensuring accuracy and reliability in pharmacokinetic and metabolic studies. It is essential for researchers and manufacturers in the pharmaceutical and analytical chemistry sectors who require high-purity, stable-isotope labeled materials for method development, validation, and quality control of antifungal drug products.

Application

• Primary use as a stable-isotope labeled internal standard for the quantification of lanoconazole in biological matrices via LC-MS/MS.
• Critical component in pharmacokinetic and bioequivalence studies for antifungal drug development.
• Reference material for method validation and quality control in pharmaceutical analysis.
• Used in drug metabolism and disposition studies to track and differentiate the parent compound from metabolites.
• Essential for regulatory submissions to agencies like the FDA and EMA, providing definitive analytical data.
• Research tool in dermatological and antifungal research involving mechanistic and efficacy studies.

Basic Information

Product Name	Lanoconazole-D3
CAS No.	1185241-05-7
Molecular Formula	C14H10D3ClN2S2
Molecular Weight	313.84 g/mol (for deuterated form)
Synonyms	Lanoconazole-d3; (R)-Lanoconazole-d3; NND-318-d3; (±)-Lanoconazole-d3; 1-[(R)-2-[(2,4-Dichlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole-d3; 1-[2-[(2,4-Dichlorophenyl)thio]-2-(2,4-dichlorophenyl)ethyl]imidazole-d3; Astat; Astat (pharmaceutical); Lanoconazole (D3)
EINECS	Contact for details

Quality Control

Our Lanoconazole-D3 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment, and impurity profiles. We adhere to relevant industry standards for reference materials, and our quality commitment ensures reliability for your most sensitive LC-MS/MS methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.