Description

(2-Quinoxalinylmethylene)Hydrazinecarboxylic Acid Methyl-D3 Ester N,N'-Dioxide is a deuterated derivative of a quinoxaline-based compound, serving as a crucial analytical standard and research chemical. Its primary value lies in its use as a stable isotope-labeled internal standard for precise quantification in mass spectrometry, ensuring high analytical accuracy and reliability. This compound is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors, particularly for method development, pharmacokinetic studies, and metabolite identification.

Application

• Primary use as a deuterium-labeled internal standard (IS) for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis.
• Critical component in quantitative bioanalysis for drug discovery and development, enabling accurate measurement of parent compounds and metabolites.
• Supporting pharmacokinetic (PK) and toxicokinetic (TK) studies by minimizing matrix effects and improving data precision.
• Use in environmental fate studies and residue analysis for agrochemicals and related compounds.
• Application in metabolite identification and profiling research within pharmaceutical R&D.
• Calibration and validation of analytical methods to meet GLP (Good Laboratory Practice) and regulatory compliance requirements (e.g., FDA, EMA).
• Research into the chemical properties and reactivity of functionalized quinoxaline N,N'-dioxide systems.

Basic Information

Product Name	(2-Quinoxalinylmethylene)Hydrazinecarboxylic Acid Methyl-D3 Ester N,N'-Dioxide
CAS No.	1185240-06-5
Molecular Formula	C11H6D3N5O4
Molecular Weight	~274.23 g/mol
Synonyms	Methyl-d3 (2-quinoxalinylmethylene)hydrazinecarboxylate N,N'-dioxide; (Quinoxalin-2-ylmethylene)hydrazinecarboxylic acid methyl-d3 ester 1,4-dioxide; Deuterated Quinoxaline Hydrazide N-Oxide; Methyl-d3 ester of (2-quinoxalinylmethylene)hydrazinecarboxylic acid N,N'-dioxide; 2-Quinoxalinecarboxaldehyde, [(methoxy-d3carbonyl)hydrazone] N,N'-dioxide; Internal Standard for Quinoxaline Analysis; CAS 1185240-06-5.
EINECS	Contact for details

Quality Control

Every batch of our deuterated analytical standards is produced and verified under a strict quality management system. We guarantee high chemical and isotopic purity, confirmed by advanced spectroscopic and chromatographic techniques including NMR, HPLC, and LC-MS. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific data on purity, isotopic enrichment (D3), and identity. Our production adheres to relevant guidelines for research and diagnostic materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing under inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (D3, MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.