Description

Stiripentol-D9 is a deuterated isotopologue of the anticonvulsant drug Stiripentol, specifically labeled with nine deuterium atoms. This stable-labeled internal standard is critical for ensuring the accuracy and reliability of quantitative bioanalytical methods, such as LC-MS/MS, in pharmacokinetic and metabolism studies. It is an essential tool for pharmaceutical R&D laboratories, clinical research organizations, and regulatory bodies focused on the development and therapeutic monitoring of antiepileptic medications.

Application

• Primary use as a stable isotope-labeled internal standard for the precise quantification of Stiripentol in biological matrices (plasma, serum, urine).
• Enabling high-accuracy pharmacokinetic (PK) and bioavailability studies during drug development and clinical trials.
• Critical component in LC-MS/MS method development and validation for therapeutic drug monitoring (TDM) in epilepsy treatment.
• Supporting metabolite identification and profiling studies to understand drug metabolism pathways.
• Used in forensic and anti-doping analysis for the definitive identification and measurement of Stiripentol.
• Facilitating regulatory submissions by providing data that meets stringent FDA and EMA guidelines for bioanalytical method validation.

Basic Information

Product Name	Stiripentol-D9
CAS No.	1185239-64-8
Molecular Formula	C14H9D9O3
Molecular Weight	249.34 g/mol (approx.)
Synonyms	Stiripentol-d9; Diacomit-d9; (E)-1-(1,3-Benzodioxol-5-yl)-4,4,4-trideuterio-4-(2,3,5,6-tetradeuteriophenyl)but-1-en-3-one-2,2,3,3-d4; BCX 2600-d9; 4,4-Dideutero-1-(2,3-methylenedioxyphenyl)-4-(2,3,5,6-tetradeuteriophenyl)-1-buten-3-one-2,2,3,3-d4
EINECS	Contact for details

Quality Control

Our Stiripentol-D9 is manufactured under strict quality control protocols to ensure the high chemical and isotopic purity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for identity, assay, isotopic enrichment, and purity by HPLC. We ensure compliance with relevant standards for stable labeled compounds used in regulated bioanalysis.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥98.0 atom % D
Chemical Purity	≥95.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.