Description

(E/Z)-4-(4'-Hydroxyphenyl)-2-Butanone-D5 Oxime is a deuterated isotopologue of raspberry ketone oxime, a key intermediate in flavor and fragrance synthesis. This compound matters for its utility as a stable, non-radioactive isotopic tracer in advanced analytical and metabolic studies, providing critical insights into biochemical pathways. It is primarily needed by research institutions and chemical manufacturers specializing in high-value flavor compounds, fragrance development, and pharmaceutical research where deuterium labeling is required for mass spectrometry and NMR spectroscopy.

Application

• Flavor and Fragrance Research: As a deuterated standard for the accurate quantification of raspberry ketone and its metabolites in complex matrices.
• Pharmaceutical Development: Used as a labeled intermediate in the synthesis of deuterated drug candidates for pharmacokinetic and metabolic stability studies.
• Analytical Chemistry: Serves as an internal standard in LC-MS and GC-MS methods to ensure precision and accuracy in flavor, food, and environmental analysis.
• Biochemical Tracing: Enables the study of absorption, distribution, metabolism, and excretion (ADME) pathways of phenolic compounds in biological systems.
• Organic Synthesis: A specialized building block for synthesizing deuterated analogs of natural products and aroma chemicals.

Basic Information

Product Name	(E/Z)-4-(4'-Hydroxyphenyl)-2-Butanone-D5 Oxime
CAS No.	1185238-88-3
Molecular Formula	C10H6D5NO2
Molecular Weight	182.23 g/mol (for D5 isotopologue)
Synonyms	Raspberry Ketone Oxime-d5; 4-(4-Hydroxyphenyl)-2-butanone Oxime-d5; p-Hydroxybenzylacetone Oxime-d5; (E/Z)-4-(4-Hydroxyphenyl)butan-2-one Oxime-d5; Oxyphenylon Oxime-d5; Frambinon Oxime-d5; Rheosmin Oxime-d5; (E/Z)-1-[4-(Hydroxyphenyl)]-3-buten-2-one Oxime-d5
EINECS	Contact for details

Quality Control

Our (E/Z)-4-(4'-Hydroxyphenyl)-2-Butanone-D5 Oxime is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity (D-enrichment) and chemical identity. Certificates of Analysis (COA) detailing assay, isomeric ratio (E/Z), and impurity profiles are provided to ensure compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (D5 pattern)
Purity (HPLC)	≥ 98.0%
Isomeric Ratio (E/Z) (HPLC)	Specified on COA
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.