Description

2,6-Di-(tert-Butyl-D9)-4-Methoxyphenol is a deuterated analog of the common antioxidant butylated hydroxyanisole (BHA). This compound is specifically designed for use as an internal standard in analytical chemistry, enabling precise quantification and method validation in complex matrices. It is essential for researchers and quality control laboratories in the pharmaceutical, food science, and polymer industries who require high-fidelity analytical standards for mass spectrometry and chromatography.

Application

• Analytical Internal Standard: Primary use as a deuterated internal standard for the accurate quantification of BHA and related phenolic antioxidants via GC-MS or LC-MS.
• Pharmaceutical Research: Used in stability studies and pharmacokinetic research to track the metabolism and degradation of antioxidant excipients in drug formulations.
• Food & Beverage Analysis: Critical for regulatory testing and quality assurance to measure antioxidant preservative levels in food products and packaging materials.
• Polymer & Material Science: Employed in research to study the efficiency and migration of stabilizers in plastics, rubbers, and lubricants.
• Metabolomics & Biomarker Discovery: Serves as a stable isotope-labeled tracer in metabolic pathway analysis and environmental fate studies.
• Method Development & Validation: A key reagent for developing, calibrating, and validating official analytical methods in compliance with FDA, EPA, or pharmacopeial guidelines.

Basic Information

Product Name	2,6-Di-(tert-Butyl-D9)-4-Methoxyphenol
CAS No.	1185162-50-8
Molecular Formula	C16D9H15O2
Molecular Weight	257.38 g/mol (deuterated form)
Synonyms	BHA-d9; 2,6-Bis(tert-butyl-d9)-4-methoxyphenol; Deuterated Butylated Hydroxyanisole; 3,5-Di-tert-butyl-4-hydroxyanisole-d9; 2,6-Di-tert-butyl-4-methoxyphenol-d9; (D9)-BHA; tert-Butyl-d9 BHA; Internal Standard for BHA; EINECS Contact for details

Quality Control

Our 2,6-Di-(tert-Butyl-D9)-4-Methoxyphenol is manufactured under strict quality systems to ensure the high isotopic purity and chemical integrity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-enrichment), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant standards for high-purity reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.