Description

3,4,5-Trimethoxy-D9-2'-Cyano-Di-Hydrocinnamaldehyde Dimethylacetal is a high-purity, deuterium-labeled advanced intermediate used in the synthesis of complex organic molecules. Its core value lies in providing a stable, isotopically enriched building block for research and development, enabling precise metabolic and pharmacokinetic studies. This compound is essential for pharmaceutical R&D scientists, agrochemical researchers, and analytical chemists working on the development of new active ingredients, particularly where deuterium labeling is required for tracing or to modify biological activity.

Application

• Pharmaceutical Research & Development: A critical deuterated intermediate for synthesizing labeled drug candidates, metabolites, and internal standards for bioanalytical methods (LC-MS/MS).
• Agrochemical Innovation: Used in the discovery and development of novel, labeled pesticides and herbicides to study environmental fate and degradation pathways.
• Metabolic Pathway Tracing: Enables detailed investigation of drug metabolism and biochemical pathways due to its stable deuterium atoms.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for quantitative analysis in complex matrices.
• Medicinal Chemistry: Provides a versatile synthon for constructing complex molecular architectures containing the trimethoxyphenyl and cyano functional groups.
• Isotope Effect Studies: Facilitates research into kinetic isotope effects (KIEs) to understand reaction mechanisms in chemical and biological systems.

Basic Information

Product Name	3,4,5-Trimethoxy-D9-2'-Cyano-Di-Hydrocinnamaldehyde Dimethylacetal
CAS No.	1185144-63-1
Molecular Formula	C₁₅D₉H₁₂NO₅
Molecular Weight	~307.33 g/mol (deuterated form)
Synonyms	2-(3,4,5-Trimethoxyphenyl)-3-(dimethoxymethyl)-3-cyanopropane-d9; 3,4,5-Trimethoxy-D9-benzaldehyde cyanohydrin dimethyl acetal; (3,4,5-Trimethoxyphenyl)-D9-propanedinitrile dimethyl acetal derivative; Deuterated Trimethoxycinnamaldehyde Cyanohydrin Dimethyl Acetal; D9-TMCDA (abbreviation); 1185144-63-1; Perdeuterated TMCDA
EINECS	Contact for details

Quality Control

Every batch of 3,4,5-Trimethoxy-D9-2'-Cyano-Di-Hydrocinnamaldehyde Dimethylacetal is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, with specifications typically covering identity (NMR, IR), assay (HPLC), deuterium incorporation (MS), and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.