Description

Methyl Imidazol-1-Yl-Acetate-D3 is a deuterated derivative of a key imidazole-based building block, where three hydrogen atoms are replaced with deuterium, a stable isotope. This deuteration is crucial for enhancing metabolic stability and traceability in research, making it a valuable tool for pharmacokinetic and mechanistic studies. It is primarily sought by pharmaceutical R&D and agrochemical scientists for use as an advanced intermediate in the synthesis of deuterated active pharmaceutical ingredients (APIs) and other labeled compounds.

Application

• Deuterated Pharmaceutical Intermediate: A critical building block for synthesizing deuterium-labeled drug candidates, leveraging the kinetic isotope effect to potentially improve metabolic profiles.
• Agrochemical Research: Used in the development of novel, labeled agrochemicals for studying environmental fate, degradation pathways, and residue analysis.
• Metabolic Pathway Tracing: Serves as a stable isotope-labeled precursor in mass spectrometry-based studies to track drug metabolism and distribution in biological systems.
• Material Science Research: Employed in the synthesis of specialized polymers or organic electronic materials where isotopic labeling is required for structural analysis.
• Analytical Reference Standard: Used as an internal standard in quantitative LC-MS/MS analysis for accurate measurement of its non-deuterated counterpart in complex matrices.

Basic Information

Product Name	Methyl Imidazol-1-Yl-Acetate-D3
CAS No.	1185134-32-0
Molecular Formula	C7H6D3N2O2
Molecular Weight	156.18 g/mol (approx.)
Synonyms	Methyl 1H-Imidazol-1-ylacetate-d3; 1H-Imidazol-1-yl-acetic Acid Methyl Ester-d3; (1H-Imidazol-1-yl)acetic Acid Methyl Ester-d3; Methyl (Imidazol-1-yl)acetate-d3; Methyl (1H-Imidazol-1-yl)acetate-d3; Deuterated Methyl Imidazolylacetate; [D3]-Methyl Imidazol-1-ylacetate
EINECS	Contact for details

Quality Control

Our Methyl Imidazol-1-Yl-Acetate-D3 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity. A Certificate of Analysis (COA) detailing assay, isotopic enrichment (D-content), and impurity profile is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.