Description

2,3-Dihydro-5-Benzofuranethanol-D4 is a deuterium-labeled analog of a key benzofuran derivative, serving as a critical internal standard and tracer in advanced analytical chemistry. This high-purity, isotopically labeled compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) research, proteomics, and environmental analysis.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the precise quantification of its non-labeled counterpart in bioanalytical methods, minimizing matrix effects and improving data accuracy.
• Drug Metabolism Studies (DMPK): Employed as a stable isotope tracer to investigate the metabolic pathways, absorption, distribution, and excretion of pharmaceutical compounds in vivo and in vitro.
• Proteomics & Biomarker Research: Facilitates relative and absolute quantification in mass spectrometry-based proteomic workflows for discovering and validating disease biomarkers.
• Environmental Fate Analysis: Acts as a tracer in environmental science to study the degradation, transformation, and bioaccumulation of chemical pollutants.
• Synthetic Intermediate: Serves as a labeled building block for the synthesis of more complex deuterated molecules for research and diagnostic purposes.
• Quality Control & Method Development: Critical for developing, validating, and auditing analytical methods in regulatory environments to ensure compliance with GLP and GMP standards.

Basic Information

Product Name	2,3-Dihydro-5-Benzofuranethanol-D4
CAS No.	1185079-36-0
Molecular Formula	C10H8D4O2
Molecular Weight	168.22 g/mol (approx.)
Synonyms	5-(2-Hydroxyethyl)-2,3-dihydrobenzofuran-D4; 2-(2,3-Dihydrobenzofuran-5-yl)ethanol-D4; 2,3-Dihydro-5-benzofuranethanol-d4; Deuterated 2,3-Dihydro-5-Benzofuranethanol; Benzofuran-5-ethanol-D4, 2,3-dihydro-; [D4]-2,3-Dihydro-5-benzofuranethanol; Stable Isotope Labeled 2,3-Dihydro-5-Benzofuranethanol
EINECS	Contact for details

Quality Control

Every batch of our 2,3-Dihydro-5-Benzofuranethanol-D4 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR (1H, 13C), mass spectrometry, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment (typically >98 atom % D), and solvent content. Our quality commitment ensures the material meets the stringent requirements for GLP/GMP-compliant research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white solid or colorless to pale yellow liquid/oil
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.