Description

Vedaprofen-D3 CAS NO 1185054-34-5 is a deuterated analog of the non-steroidal anti-inflammatory drug (NSAID) vedaprofen, specifically labeled with three deuterium atoms. This stable isotope-labeled compound is a critical tool for advanced pharmacokinetic and metabolic studies, providing enhanced analytical sensitivity and reliability. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug development and bioanalytical research.

Application

• As an internal standard for the precise quantification of vedaprofen in biological matrices using LC-MS/MS and GC-MS methods.
• For conducting deuterium isotope effect studies to investigate metabolic pathways and enzyme mechanisms.
• In pharmacokinetic (PK) and bioavailability studies to ensure accurate and reliable data.
• Use in drug metabolism and disposition (DMPK) research to trace and identify metabolites.
• Application in quality control and method validation within analytical laboratories.
• As a key material for the development and calibration of diagnostic assays.

Basic Information

Product Name	Vedaprofen-D3
CAS No.	1185054-34-5
Molecular Formula	C19H20D3NO3
Molecular Weight	~314.41 g/mol
Synonyms	4-(1-Oxo-2-isoindolinyl)-α-methylbenzeneacetic-2,3,4-d3 acid; Vedaprofen-d3; Deuterated Vedaprofen; [2H3]-Vedaprofen; 2-(4-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl)propionic-2,3,4-d3 acid; UNII-8JQ5607E5S (deuterated form)
EINECS	Contact for details

Quality Control

Our Vedaprofen-D3 is manufactured under strict quality systems to ensure high chemical and isotopic purity, essential for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), isotopic enrichment, and identification. We adhere to relevant industry standards for fine chemicals and stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.