Description

3’-Acetyl-4’-(2,3-Epoxypropoxy-D5)-Butyranilide is a deuterated chemical intermediate of significant importance in advanced pharmaceutical research and development. This compound is specifically designed for use in drug metabolism and pharmacokinetic (DMPK) studies, where its deuterium-labeled structure provides critical insights. It is primarily utilized by research scientists and process chemists in the pharmaceutical and biotechnology industries for the development of novel therapeutic agents. The compound's specialized structure makes it a valuable tool for tracing and understanding biological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated active pharmaceutical ingredients (APIs) for improved metabolic stability.
• Metabolic Tracer: Used in DMPK studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of drug candidates.
• Isotope Labeling Agent: Employed in the preparation of isotopically labeled standards for use in quantitative mass spectrometry (LC-MS/MS) analysis.
• Mechanistic Probe: Facilitates research into reaction mechanisms and biological pathways within medicinal chemistry programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Item	Details
Product Name	3’-Acetyl-4’-(2,3-Epoxypropoxy-D5)-Butyranilide
CAS No.	1185052-79-2
Molecular Formula	C15H14D5NO4
Molecular Weight	Contact for details
Synonyms	Deuterated Glycidyl Butyranilide Derivative; 4'-(2,3-Epoxypropoxy-d5)-3'-acetylbutyranilide; N-[4-[(2,3-Epoxypropoxy-d5)]-3-acetylphenyl]butyramide; Butyranilide, 3'-acetyl-4'-(2,3-epoxypropoxy-d5)-; Deuterated Epoxy Intermediate; Deuterated API Intermediate; Isotope Labeled Anilide
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the integrity of our advanced intermediates. Each batch of 3’-Acetyl-4’-(2,3-Epoxypropoxy-D5)-Butyranilide is analyzed using state-of-the-art techniques including NMR and HPLC to confirm identity, chemical purity, and isotopic enrichment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality commitment supports compliance with the stringent requirements of cGMP for investigational products and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D-content)	≥ 95 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.