Description

3,4-Dihydro-2H-Quinoxaline-1,7-Dicarboxylic Acid 1-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoxaline core and protected carboxylic acid functionality. This compound is essential for synthetic chemists developing novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile building block for complex molecular architectures. It is primarily utilized in research and development for the synthesis of heterocyclic compounds with potential applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents with improved efficacy and safety profiles.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing fused heterocyclic systems, enabling the exploration of novel chemical space in academic and industrial R&D.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and high-value materials that require a defined quinoxaline scaffold.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target engagement within cellular systems.

Basic Information

Product Name	3,4-Dihydro-2H-Quinoxaline-1,7-Dicarboxylic Acid 1-tert-Butyl Ester
CAS No.	1185051-01-7
Molecular Formula	C15H18N2O4
Molecular Weight	290.31 g/mol
Synonyms	1-tert-Butyl 3,4-dihydro-2H-quinoxaline-1,7-dicarboxylate; 1-(tert-Butoxycarbonyl)-3,4-dihydroquinoxaline-7-carboxylic Acid; 1-Boc-3,4-dihydroquinoxaline-7-carboxylic Acid; 7-Carboxy-1-Boc-1,2,3,4-tetrahydroquinoxaline; 1-tert-Butyl 7-carboxy-3,4-dihydro-2H-quinoxaline-1-carboxylate; 1185051-01-7; Quinoxaline-1,7-dicarboxylic acid, 3,4-dihydro-2H-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to a quality management system to support our commitment to supplying reliable, high-grade intermediates for demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.