Description

2-Methyl-D3-2-Propyl-1,3-Propanediol is a deuterium-labeled analog of a branched-chain diol, serving as a critical stable isotope-labeled intermediate. Its primary value lies in enabling precise metabolic and pharmacokinetic studies through mass spectrometry and NMR, where it acts as an internal standard to ensure analytical accuracy. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require high-fidelity isotopic tracers for development and quality control.

Application

• Pharmaceutical Research & Development: Used as a stable isotope-labeled internal standard in LC-MS and GC-MS for the quantitative bioanalysis of drug candidates and metabolites.
• Metabolic Pathway Tracing: Employed in deuterium labeling studies to investigate biochemical pathways and drug metabolism in vivo.
• Polymer Science: Acts as a deuterated monomer or chain extender in the synthesis of specialty polymers for analytical and structural studies.
• Agrochemical Development: Serves as a labeled standard in the environmental fate and residue analysis of pesticides and herbicides.
• NMR Spectroscopy: Provides a non-radioactive, stable isotopic probe for detailed molecular structure elucidation and dynamics studies.
• Chemical Synthesis: Functions as a building block for synthesizing more complex deuterated compounds where the labeled methyl and propyl groups are required.

Basic Information

Product Name	2-Methyl-D3-2-Propyl-1,3-Propanediol
CAS No.	1185023-23-7
Molecular Formula	C7H11D3O2
Molecular Weight	133.21 g/mol
Synonyms	2-Methyl-2-(propyl-d3)-1,3-propanediol; 2-(Methyl-d3)-2-propylpropane-1,3-diol; 2-Propyl-2-(methyl-d3)-1,3-propanediol; Deuterated Neopentyl Glycol Derivative; (2-Methyl-d3-2-propyl)trimethylene glycol; 1,3-Propanediol, 2-methyl-2-propyl-, 2-methyl-d3-; D3-Labeled 2-Methyl-2-propyl-1,3-propanediol
EINECS	Contact for details

Quality Control

Our 2-Methyl-D3-2-Propyl-1,3-Propanediol is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-enrichment), chemical purity by HPLC/GC, and identity confirmation by NMR and IR spectroscopy. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of water vapor. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D (at labeled positions)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.