Description

Imidazol-1-Yl-Acetic Acid-15N2,13C2 is a stable isotope-labeled derivative of imidazole-1-yl-acetic acid, specifically enriched with carbon-13 and nitrogen-15 at key positions. This compound is essential as a high-purity internal standard and tracer in quantitative mass spectrometry and metabolic pathway analysis, providing unmatched accuracy for research and diagnostic applications. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and advanced analytical service providers engaged in proteomics, metabolomics, and pharmacokinetic studies.

Application

• Internal Standard for LC-MS/MS quantification of imidazole derivatives and related metabolites in biological matrices.
• Tracer in metabolic flux analysis and stable isotope-resolved metabolomics (SIRM) studies.
• Critical reagent for developing and validating bioanalytical methods in drug discovery and development.
• Use in nuclear magnetic resonance (NMR) spectroscopy as a labeled reference compound.
• Research into enzyme kinetics and mechanistic studies involving histidine metabolism or related pathways.
• Production of labeled active pharmaceutical ingredients (APIs) or intermediates for clinical tracer studies.

Basic Information

Product Name	Imidazol-1-Yl-Acetic Acid-15N2,13C2
CAS No.	1184983-00-3
Molecular Formula	C413C2H6N15N2O2
Molecular Weight	Contact for details
Synonyms	1H-Imidazol-1-ylacetic-1,2-13C2,1',3'-15N2 acid; (1H-Imidazol-1-yl)acetic-1,2-13C2,1',3'-15N2 Acid; Isotopically Labeled Imidazole-1-acetic Acid; [13C2,15N2]-Imidazol-1-ylacetic Acid; 1-Imidazolylacetic-13C2,15N2 Acid; IAA-13C2,15N2; Stable Isotope-Labeled IAA
EINECS	Contact for details

Quality Control

Every batch of Imidazol-1-Yl-Acetic Acid-15N2,13C2 is manufactured and analyzed under strict quality systems to ensure isotopic and chemical purity meets the exacting standards required for analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment (Atom % 13C and 15N), chemical purity, and identity confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Isotopic Enrichment (15N)	≥ 99 atom % 15N
Chemical Purity (NMR)	≥ 97%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.