Description

1-[(tert-Butyldimethylsilyl)Oxy]-2-Methyl-2-Acetoxypropanol-D6 is a high-purity, deuterium-labeled derivative of a protected diol, serving as a critical stable isotope-labeled intermediate. This compound is specifically engineered to provide unmatched traceability and reliability in advanced analytical and synthetic workflows. It is an essential material for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise isotopic labeling for metabolic studies, internal standards, and mechanistic investigations.

Application

• Deuterated Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development for pharmacokinetic and metabolomic studies.
• Pharmaceutical Intermediate: A key building block in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) for drug discovery and development.
• Metabolic Pathway Tracing: Enables the study of drug metabolism and biochemical pathways using mass spectrometry due to its stable isotopic label.
• Agrochemical Research: Employed in the development and analysis of novel, labeled agrochemical compounds and their environmental fate.
• NMR Spectroscopy: Acts as a useful probe or solvent additive in nuclear magnetic resonance studies.
• Chemical Synthesis: Utilized in multi-step organic synthesis where a protected, labeled diol functionality is required.

Basic Information

Product Name	1-[(tert-Butyldimethylsilyl)Oxy]-2-Methyl-2-Acetoxypropanol-D6
CAS No.	1184976-30-4
Molecular Formula	C12H18D6O4Si
Molecular Weight	278.45 g/mol
Synonyms	2-Methyl-2-acetoxy-1-[(tert-butyldimethylsilyl)oxy]propanol-d6; 1-[(Tert-butyldimethylsilyl)oxy]-2-methyl-2-(acetyloxy)propanol-d6; Deuterated TBDMS-protected diol acetate; 2-Methyl-2-(acetyloxy)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-propanol-d6; 1-Propanol, 2-methyl-2-(acetyloxy)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, 1,1,1,3,3,3-d6; TBDMS ether of deuterated acetoxy isobutyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 1-[(tert-Butyldimethylsilyl)Oxy]-2-Methyl-2-Acetoxypropanol-D6 is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including isotopic purity and chemical purity assays, to ensure compliance with the high standards required for research and cGMP applications. Certificates of Analysis (COA) detailing batch-specific results from NMR, HPLC, and MS are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.