Description

5-Bromo-n-(4,4,5,5-Tetradeuterio-1H-Imidazol-2-Yl)Quinoxalin-6-Amine is a deuterated heterocyclic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical building block for creating isotopically labeled drug candidates and biochemical probes, enabling detailed metabolic and pharmacokinetic studies. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical sectors who require high-purity, specialized intermediates for tracer applications and structure-activity relationship (SAR) optimization.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of deuterated drug molecules, particularly in oncology and CNS therapeutic areas.
• Metabolic Tracer: Used in Drug Metabolism and Pharmacokinetics (DMPK) studies to track the fate of drug molecules in biological systems via Mass Spectrometry (MS).
• Biochemical Probe Development: Serves as a precursor for labeled probes used in mechanistic enzymology and receptor binding assays.
• Agrochemical Research: Employed in the development of novel, isotopically labeled pesticides and herbicides for environmental fate studies.
• Academic Research: Used in universities and research institutes for fundamental studies in medicinal chemistry and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D with custom synthesis and labeling services.

Basic Information

Product Name	5-Bromo-n-(4,4,5,5-Tetradeuterio-1H-Imidazol-2-Yl)Quinoxalin-6-Amine
CAS No.	1184971-51-4
Molecular Formula	C11H7BrD4N5
Molecular Weight	306.18 g/mol
Synonyms	5-Bromo-N-(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)quinoxalin-6-amine; 6-Amino-5-bromo-N-(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)quinoxaline; 5-Bromo-6-((4,4,5,5-tetradeuterio-1H-imidazol-2-yl)amino)quinoxaline; Deuterated 5-Bromo-imidazoquinoxaline amine; [D4]-5-Bromo-N-(1H-imidazol-2-yl)quinoxalin-6-amine; 1184971-51-4; BRD4-labeled quinoxaline derivative
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(4,4,5,5-Tetradeuterio-1H-Imidazol-2-Yl)Quinoxalin-6-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C), HPLC, and Mass Spectrometry, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.