Description

8-Chloroisoquinolin-3-Amine is a versatile and high-value heterocyclic building block with significant importance in advanced organic synthesis. This compound is a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its reactive amine and halogen functionalities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and production of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology: Utilized as a probe or tagging molecule in biochemical research and assay development.
• Academic & Industrial R&D: A fundamental building block for methodological studies in organic chemistry and scale-up process development.

Basic Information

Product Name	8-Chloroisoquinolin-3-Amine
CAS No.	1184843-26-2
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	3-Amino-8-chloroisoquinoline; 8-Chloro-3-isoquinolinamine; 8-Chloroisoquinolin-3-ylamine; 8-Chloro-3-aminoisoquinoline; 3-Isoquinolinamine, 8-chloro-; 1184843-26-2; 8-Cl-IQ-3-NH2
EINECS	Contact for details

Quality Control

Our 8-Chloroisoquinolin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.