Description

1-(3,4-Difluorophenyl)-2-Methylpropan-1-Ol is a high-purity fluorinated alcohol intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the difluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display and lighting materials, improving performance characteristics.
• Advanced Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties, solubility, and chemical resistance.
• Chiral Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis due to its defined stereochemistry.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Item	Detail
Product Name	1-(3,4-Difluorophenyl)-2-Methylpropan-1-Ol
CAS No.	1184394-61-3
Molecular Formula	C10H12F2O
Molecular Weight	186.20 g/mol
Synonyms	1-(3,4-Difluorophenyl)-2-methyl-1-propanol; α,α-Dimethyl-3,4-difluorobenzyl alcohol; 2-Methyl-1-(3,4-difluorophenyl)propan-1-ol; (3,4-Difluorophenyl)(isopropyl)methanol; 3,4-Difluoro-α-(1-methylethyl)benzenemethanol; 1-(3,4-Difluorophenyl)-2-methylpropanol
EINECS	Contact for details

Quality Control

Our 1-(3,4-Difluorophenyl)-2-Methylpropan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Specific enantiomer available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.