Description

4-Bromo-1-(2-Methanesulfonylethyl)-1H-Pyrazole is a high-value, functionalized pyrazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and process chemists in pharmaceutical R&D, agrochemical synthesis, and material science who require precise bromination and sulfonylethyl functionalization for structure-activity relationship (SAR) studies and lead optimization.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the pyrazole core for biological activity.
• Chemical Research & Development: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Sonogashira) and further functionalization in academic and industrial labs.
• Material Science Precursor: Employed in the synthesis of specialized ligands for catalysis or functional organic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-purity heterocyclic intermediates.

Basic Information

Product Name	4-Bromo-1-(2-Methanesulfonylethyl)-1H-Pyrazole
CAS No.	1183252-85-8
Molecular Formula	C6H9BrN2O2S
Molecular Weight	265.12 g/mol
Synonyms	4-Bromo-1-(2-methanesulfonylethyl)-1H-pyrazole; 1H-Pyrazole, 4-bromo-1-[2-(methylsulfonyl)ethyl]-; 4-Bromo-1-[2-(methylsulfonyl)ethyl]pyrazole; 4-Bromo-1-(2-methylsulfonylethyl)pyrazole; 1183252-85-8; 4-Br-1-MSE-Pyrazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(2-Methanesulfonylethyl)-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended long-term storage at 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.