Description

3-(2-Chlorophenyl)Cyclobutanol CAS NO 1182960-42-4 is a specialized organic compound featuring a cyclobutanol ring substituted with a 2-chlorophenyl group, making it a valuable chiral building block and intermediate in synthetic chemistry. This compound matters for its structural rigidity and functional handles, which are critical for constructing complex molecular architectures with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the chlorophenyl and cyclobutanol motifs contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of monomers and specialty polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: A versatile building block in medicinal chemistry and process chemistry for exploring new synthetic routes and compound libraries.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	3-(2-Chlorophenyl)Cyclobutanol
CAS No.	1182960-42-4
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	3-(2-Chlorophenyl)cyclobutan-1-ol; 2-Chloro-α-(1-hydroxycyclobutyl)benzene; Cyclobutanol, 3-(2-chlorophenyl)-; 1-(2-Chlorophenyl)cyclobutanol; (3-(2-Chlorophenyl)cyclobutyl)methanol (isomer); 1182960-42-4
EINECS	Contact for details

Quality Control

Our 3-(2-Chlorophenyl)Cyclobutanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.