Description

Methyl 3,4,5-Trimethoxy-D9-Benzoate CAS NO 1182838-07-8 is a high-purity, deuterium-labeled derivative of methyl gallate, featuring nine deuterium atoms for enhanced stability and traceability in analytical applications. This compound is a critical stable isotope-labeled standard, providing unmatched precision for quantitative analysis and metabolic studies. It is primarily required by research institutions and pharmaceutical companies engaged in advanced analytical chemistry, pharmacokinetics, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of its non-deuterated counterpart or related metabolites.
• Pharmaceutical Research & Development: Essential in drug metabolism and pharmacokinetics (DMPK) studies as a tracer to investigate absorption, distribution, metabolism, and excretion (ADME) pathways.
• Deuterated API Synthesis: Serves as a key synthetic intermediate or precursor in the production of deuterium-labeled drug molecules, which can offer improved metabolic stability.
• Analytical Method Development & Validation: Employed to develop, calibrate, and validate highly sensitive and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, ICH).
• Biochemical Tracing: Utilized in mechanistic studies to trace biochemical pathways and enzymatic transformations without interference from endogenous compounds.
• Quality Control & Reference Material: Acts as a certified reference material (CRM) for ensuring the accuracy and reliability of analytical results in quality control laboratories.

Basic Information

Product Name	Methyl 3,4,5-Trimethoxy-D9-Benzoate
CAS No.	1182838-07-8
Molecular Formula	C11D9H2O5
Molecular Weight	229.25 g/mol
Synonyms	Methyl Gallate-d9 Trimethyl Ether; Methyl 3,4,5-Trimethoxybenzoate-d9; Benzoic acid, 3,4,5-trimethoxy-, methyl ester-d9; Deuterated Methyl Trimethoxybenzoate; (2,3,4,5,6-Pentadeuterio-3,4,5-trimethoxyphenyl)methyl-d4 Formate; Gallic Acid Trimethyl Ether Methyl Ester-d9; Methyl 3,4,5-Trimethoxybenzoate (phenyl-D5, methyl-D4)
EINECS	Contact for details

Quality Control

Every batch of Methyl 3,4,5-Trimethoxy-D9-Benzoate is manufactured under strict quality systems and undergoes comprehensive analytical testing to ensure high chemical purity and isotopic enrichment. We provide full traceability and compliance documentation. A detailed Certificate of Analysis (COA) specifying purity by HPLC/NMR, isotopic purity (D-content), and other critical parameters is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.