Description

4-Cyanobenzo[B]Thiophene-2-Carboxylic Acid CAS NO 1182349-12-7 is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a benzo[b]thiophene core with both carboxylic acid and nitrile functional groups, enabling diverse chemical modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic semiconductors and non-linear optical (NLO) materials.
• Chemical Synthesis: Utilized as a versatile synthon in medicinal chemistry for constructing complex fused-ring systems via reactions at the carboxylic acid or nitrile group.
• Ligand & Catalyst Development: The functional groups allow for its use in designing novel ligands for metal catalysis or organocatalysts.

Basic Information

Product Name	4-Cyanobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	1182349-12-7
Molecular Formula	C10H5NO2S
Molecular Weight	203.22 g/mol
Synonyms	4-Cyanobenzo[b]thiophene-2-carboxylic acid; 2-Carboxy-4-cyanobenzo[b]thiophene; 4-Cyano-1-benzothiophene-2-carboxylic acid; 4-CN-BT-2-COOH; Benzo[b]thiophene-2-carboxylic acid, 4-cyano-; 1182349-12-7; 4-Cyanobenzo[b]thienyl-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 4-Cyanobenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.