Description

1-(4-Bromo-1H-Indol-3-Yl)-2,2,2-Trichloroethanone is a specialized halogenated indole derivative that serves as a high-value synthetic intermediate in advanced organic chemistry. This compound is critical for constructing complex molecular architectures, offering a reactive ketone handle and a bromo-substituted indole core for selective functionalization. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel bioactive compounds, including potential drug candidates and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based drug candidates, particularly in oncology and CNS research.
• Agrochemical Research: Used in developing new generation pesticides and herbicides with specific biological activity.
• Material Science: Serves as a precursor for organic electronic materials and advanced polymers.
• Academic & R&D: Employed in methodological studies and as a standard in heterocyclic and organohalogen chemistry research.
• Chemical Biology: Useful for creating molecular probes and labeled compounds for biochemical studies.

Basic Information

Product Name	1-(4-Bromo-1H-Indol-3-Yl)-2,2,2-Trichloroethanone
CAS No.	1182349-06-9
Molecular Formula	C10H5BrCl3NO
Molecular Weight	341.41 g/mol
Synonyms	4-Bromo-1H-indol-3-yl trichloromethyl ketone; 2,2,2-Trichloro-1-(4-bromo-1H-indol-3-yl)ethanone; 1-(4-Bromoindol-3-yl)-2,2,2-trichloroethanone; 4-Bromo-3-(trichloroacetyl)indole; 3-(Trichloroacetyl)-4-bromoindole; 4-Bromo-α,α,α-trichloro-1H-indole-3-acetophenone; TCA-4-Br-Indole
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-1H-Indol-3-Yl)-2,2,2-Trichloroethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.