Description

3-Azabicyclo[4.1.0]Heptane-1-Carboxylic Acid Hydrochloride is a high-purity bicyclic amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, fused ring structure provides a valuable scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs to enhance metabolic stability and bioavailability.
• Catalyst Ligand Precursor: Useful for developing novel chiral ligands used in asymmetric catalysis.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies.

Basic Information

Product Name	3-Azabicyclo[4.1.0]Heptane-1-Carboxylic Acid Hydrochloride
CAS No.	1181458-31-0
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	1-Azabicyclo[4.1.0]heptane-3-carboxylic acid hydrochloride; 3-Carboxy-1-azabicyclo[4.1.0]heptane hydrochloride; (1R,6S)-3-Azabicyclo[4.1.0]heptane-1-carboxylic acid hydrochloride; Bicyclo[4.1.0]heptane-1-carboxylic acid, 3-aza-, hydrochloride; 3-Azabicyclo[4.1.0]heptane-1-carboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our 3-Azabicyclo[4.1.0]Heptane-1-Carboxylic Acid HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.