Description

3-[[[4-(Acetylamino)Phenyl]Thio]Methyl]-5-Amino-4-Cyano-2-Thiophenecarboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its unique thiophene and aniline-derived structure.
• Organic Electronic Materials: Acts as a building block for conjugated molecules in the research of organic semiconductors, OLEDs, or sensors due to its electron-rich thiophene core.
• Dye and Pigment Synthesis: Employed in the creation of specialized dyes and functional pigments where its amino and cyano groups offer sites for further chemical modification.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Item	Details
Product Name	3-[[[4-(Acetylamino)Phenyl]Thio]Methyl]-5-Amino-4-Cyano-2-Thiophenecarboxylic Acid Ethyl Ester
CAS No.	1180837-73-3
Molecular Formula	C18H17N3O3S2
Molecular Weight	379.47 g/mol
Synonyms	Ethyl 3-(((4-acetamidophenyl)thio)methyl)-5-amino-4-cyanothiophene-2-carboxylate; 5-Amino-3-[[(4-acetamidophenyl)thio]methyl]-4-cyano-2-thiophenecarboxylic acid ethyl ester; 3-[[(4-Acetamidophenyl)sulfanyl]methyl]-5-amino-4-cyano-2-thiophenecarboxylic acid ethyl ester; 3-(((4-Acetamidophenyl)thio)methyl)-5-amino-4-cyanothiophene-2-carboxylic acid ethyl ester; AKOS BRN 1542; A1370/0045706
EINECS	Contact for details

Quality Control

Our 3-[[[4-(Acetylamino)Phenyl]Thio]Methyl]-5-Amino-4-Cyano-2-Thiophenecarboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.