Description

(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-Acetic Acid Hydrochloride CAS NO 1179364-74-9 is a high-purity, advanced pharmaceutical intermediate belonging to the isoquinoline class of compounds. This chemical is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents, particularly within the fields of neurology and cardiovascular research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Neurological Drug Development: Used in the research and production of compounds targeting neurological pathways and receptors.
• Cardiovascular Agent Synthesis: Employed as a building block for developing potential therapeutics for cardiovascular diseases.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic & Institutional Research: Utilized in university and institutional labs for pharmacological studies and novel compound libraries.

Basic Information

Product Name	(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-Acetic Acid Hydrochloride
CAS No.	1179364-74-9
Molecular Formula	C₁₃H₁₇NO₄·HCl
Molecular Weight	287.74 g/mol
Synonyms	2-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)]acetic acid hydrochloride; (6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)acetic acid hydrochloride; 2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)acetic acid HCl; 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-acetic acid hydrochloride; Dihydroisoquinoline acetic acid derivative; Tetrahydroisoquinoline acetic acid hydrochloride; Isoquinoline intermediate 1179364-74-9
EINECS	Contact for details

Quality Control

Our (6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.