Description

3-Fluoroisoquinoline-1-Carboxylic Acid is a high-purity fluorinated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both a carboxylic acid handle and a fluorine atom, enabling precise structural modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a sophisticated ligand precursor in transition metal catalysis for asymmetric synthesis.
• Material Science: Employed in the research of organic electronic materials and fluorinated polymers with specific optical or electronic properties.
• Chemical Biology: Utilized as a probe or tag in biochemical research due to its fluorinated aromatic structure.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	3-Fluoroisoquinoline-1-Carboxylic Acid
CAS No.	1179148-90-3
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	1-Isoquinolinecarboxylic acid, 3-fluoro-; 3-Fluoro-1-isoquinolinecarboxylic acid; 3-Fluoro-isoquinoline-1-carboxylic acid; 1179148-90-3; 3-Fluoroisoquinoline-1-carboxylic acid; 3-Fluoro-1-carboxyisoquinoline; 1-Carboxy-3-fluoroisoquinoline
EINECS	Contact for details

Quality Control

Our 3-Fluoroisoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.