Description

2-Amino-2-(5-Bromo-2-Methoxy-Phenyl)-Ethanol is a specialized brominated aromatic amino alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both amino and hydroxyl functional groups adjacent to a brominated methoxyphenyl ring, makes it a versatile chiral intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of new chemical entities, particularly for central nervous system (CNS) and other therapeutic targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, auxiliaries, or catalysts used in enantioselective transformations.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to modify the physicochemical properties of drug candidates.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function or receptor binding.
• Advanced Material Synthesis: Potential building block for specialty polymers or liquid crystals requiring brominated aromatic components with functional handles.

Basic Information

Product Name	2-Amino-2-(5-Bromo-2-Methoxy-Phenyl)-Ethanol
CAS No.	1178727-53-1
Molecular Formula	C9H12BrNO2
Molecular Weight	246.10 g/mol
Synonyms	5-Bromo-2-methoxy-α-(aminomethyl)benzyl alcohol; (R/S)-2-Amino-1-(5-bromo-2-methoxyphenyl)ethanol; 1-(5-Bromo-2-methoxyphenyl)-2-aminoethanol; 2-Amino-2-(5-bromo-2-methoxyphenyl)ethan-1-ol; Amino Alcohol Derivative CAS 1178727-53-1; 5-Bromo-o-vanillyl ethanolamine
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(5-Bromo-2-Methoxy-Phenyl)-Ethanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (if applicable), and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (if applicable)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.