Description

2-(3,5-Dichlorophenyl)Thiazole-4-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate, primarily used in advanced pharmaceutical and agrochemical research and development. Its core value lies in its precise molecular architecture, which enables the construction of complex molecules with targeted biological activity. This compound is essential for medicinal chemists and process development scientists working in drug discovery, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and dichlorophenyl motifs.
• Chemical Biology & Proteomics: Serves as a versatile building block for creating molecular probes, enzyme inhibitors, and tool compounds for target identification and validation.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects under cGMP or research-grade conditions.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-(3,5-Dichlorophenyl)Thiazole-4-Carboxylic Acid
CAS No.	1178420-52-4
Molecular Formula	C10H5Cl2NO2S
Molecular Weight	274.12 g/mol
Synonyms	2-(3,5-Dichlorophenyl)-1,3-thiazole-4-carboxylic acid; 4-Thiazolecarboxylic acid, 2-(3,5-dichlorophenyl)-; 2-(3,5-Dichlorophenyl)-4-carboxythiazole; 1178420-52-4; AKOS025310065; ZINC00025310065; Thiazole-4-carboxylic acid, 2-(3,5-dichlorophenyl)-; 3,5-Dichlorophenyl thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-(3,5-Dichlorophenyl)Thiazole-4-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.