Description

2-(4-Bromo-2-Thienyl)Pyrrolidine, Hcl is a high-purity, heterocyclic organic compound featuring a pyrrolidine ring linked to a brominated thiophene moiety. This specialized chemical building block is critical for advanced research and development in medicinal chemistry, enabling the synthesis of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis or as probes in biochemical assays.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic organic chemistry and heterocyclic compound studies.
• Fine Chemical Production: Incorporated into the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-(4-Bromo-2-Thienyl)Pyrrolidine, Hcl
CAS No.	1177333-57-1
Molecular Formula	C8H10BrNS • HCl
Molecular Weight	268.59 g/mol (Free base: 232.14 g/mol)
Synonyms	2-(4-Bromothiophen-2-yl)pyrrolidine hydrochloride; 1-(4-Bromo-2-thienyl)pyrrolidine hydrochloride; Pyrrolidine, 2-(4-bromo-2-thienyl)-, hydrochloride; 4-Bromo-2-(pyrrolidin-2-yl)thiophene hydrochloride; 1177333-57-1; 2-(4-Bromo-thiophen-2-yl)-pyrrolidine HCl
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromo-2-Thienyl)Pyrrolidine, Hcl is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.