Description

1-Methyl-Indazole-5-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the indazole core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers with specific functional properties.
• Bioconjugation and Probe Synthesis: The carboxylic acid group allows for facile conjugation to biomolecules, making it useful for creating diagnostic probes and biochemical tools.

Basic Information

Product Name	1-Methyl-Indazole-5-Carboxylic Acid
CAS No.	1176754-31-6
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	1-Methyl-1H-indazole-5-carboxylic acid; 5-Carboxy-1-methylindazole; 1-Methyl-5-carboxyindazole; 1-Methylindazole-5-carboxylic acid; 1-Methyl-1H-indazole-5-carboxylic acid; 1176754-31-6; 1-Methylindazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Methyl-Indazole-5-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.