Description

5-(2,6-Dimethylphenyl)Indoline is a high-purity, advanced pharmaceutical intermediate characterized by its indoline core substituted with a 2,6-dimethylphenyl group. This compound is of significant commercial importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and agrochemical companies engaged in creating novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile indoline scaffold.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Material Science Research: Investigated as a monomer or precursor for functional organic materials and dyes.

Basic Information

Product Name	5-(2,6-Dimethylphenyl)Indoline
CAS No.	1176740-73-0
Molecular Formula	C₁₆H₁₇N
Molecular Weight	223.31 g/mol
Synonyms	5-(2,6-Dimethylphenyl)-2,3-dihydro-1H-indole; 5-(2,6-Xylyl)indoline; 1H-Indole, 2,3-dihydro-5-(2,6-dimethylphenyl)-; Indoline, 5-(2,6-dimethylphenyl)-; 5-(2,6-Dimethylphenyl)-2,3-dihydroindole
EINECS	Contact for details

Quality Control

Our 5-(2,6-Dimethylphenyl)Indoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.