Description

3-(Pyridin-3-Yl)-1H-Indazol-5-Amine CAS NO 1176535-07-1 is a high-purity heterocyclic organic compound featuring a fused indazole core substituted with an aminopyridine moiety. This specific molecular architecture makes it a valuable pharmaceutical intermediate and key building block in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and kinase inhibitor research.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Biochemical Research: Serves as a core scaffold or a functionalized ligand in the study of enzyme inhibition and protein-ligand interactions.
• Organic Synthesis: Employed in complex multi-step syntheses to introduce the privileged indazole-pyridine amine structure into target molecules.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	3-(Pyridin-3-Yl)-1H-Indazol-5-Amine
CAS No.	1176535-07-1
Molecular Formula	C12H10N4
Molecular Weight	210.24 g/mol
Synonyms	5-Amino-3-(3-pyridinyl)-1H-indazole; 3-(3-Pyridinyl)-1H-indazol-5-amine; 1H-Indazol-5-amine, 3-(3-pyridinyl)-; 3-Pyridin-3-yl-1H-indazol-5-ylamine; 5-Amino-3-(pyridin-3-yl)-1H-indazole; 3-(3-Pyridyl)-1H-indazol-5-amine; 1176535-07-1
EINECS	Contact for details

Quality Control

Our 3-(Pyridin-3-Yl)-1H-Indazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.