Description

(3Ar,5S,6As)-5-Amino-N,N,5-Trimethylhexahydrocyclopenta[C]Pyrrole-2(1H)-Carboxamide is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) targeting neurological and metabolic disorders. It is primarily utilized by pharmaceutical R&D departments and contract manufacturing organizations (CMOs) engaged in the development of novel therapeutics. The precise stereochemistry and high purity are essential for ensuring the efficacy and safety of the final drug product.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a critical chiral precursor in the scale-up and commercial manufacturing of active pharmaceutical ingredients (APIs).
• Contract Manufacturing: Supplied to CMOs and CDMOs for the production of clinical trial materials and commercial drug substances under GMP conditions.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and enzyme inhibition studies.

Basic Information

Product Name	(3Ar,5S,6As)-5-Amino-N,N,5-Trimethylhexahydrocyclopenta[C]Pyrrole-2(1H)-Carboxamide
CAS No.	1175536-07-8
Molecular Formula	C11H21N3O
Molecular Weight	211.31 g/mol
Synonyms	5-Amino-N,N,5-trimethylhexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide; (3aR,5S,6aS)-5-Amino-N,N,5-trimethylhexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide; Hexahydrocyclopenta[c]pyrrole-2-carboxamide, 5-amino-N,N,5-trimethyl-, (3aR,5S,6aS)-; CAS 1175536-07-8; Advanced Pharmaceutical Intermediate 1175536-07-8; Chiral Cyclopentapyrrolidine Carboxamide
EINECS	Contact for details

Quality Control

Our (3Ar,5S,6As)-5-Amino-N,N,5-Trimethylhexahydrocyclopenta[C]Pyrrole-2(1H)-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support development with GMP-grade material upon request, backed by full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.