Description

1-Acetyl-3-(Ethoxyphenylmethylene)-2,3-Dihydro-2-Oxo-1H-Indole-6-Carboxylic Acid Methyl Ester is a high-purity, specialized indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel bioactive molecules. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex indole-based heterocycles and studying reaction mechanisms.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Useful in the design and synthesis of molecular probes for studying biological systems and enzyme interactions.

Basic Information

Product Name	1-Acetyl-3-(Ethoxyphenylmethylene)-2,3-Dihydro-2-Oxo-1H-Indole-6-Carboxylic Acid Methyl Ester
CAS No.	1175365-43-1
Molecular Formula	C21H19NO5
Molecular Weight	365.38 g/mol
Synonyms	Methyl 1-acetyl-3-[(4-ethoxyphenyl)methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate; 6-Carbomethoxy-1-acetyl-3-(4-ethoxyphenylmethylene)-2-oxindole; 1-Acetyl-3-(4-ethoxyphenylmethylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester; 3-(4-Ethoxybenzylidene)-1-acetyl-6-(methoxycarbonyl)indolin-2-one; 1H-Indole-6-carboxylic acid, 1-acetyl-3-[(4-ethoxyphenyl)methylene]-2,3-dihydro-2-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our 1-Acetyl-3-(Ethoxyphenylmethylene)-2,3-Dihydro-2-Oxo-1H-Indole-6-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by advanced analytical techniques (HPLC, GC, NMR). Our quality system is designed to meet the stringent requirements of pharmaceutical and R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.