Description

8-(Trifluoromethyl)Isoquinolin-3-Ol is a high-value, fluorinated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold and the electron-withdrawing trifluoromethyl group, which is instrumental in modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the CF3 group enhances bioavailability and metabolic stability.
• Material Science: Acts as a building block for creating specialty chemicals, including advanced ligands for catalysis and monomers for high-performance polymers.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research due to the distinctive properties imparted by the fluorine atoms.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	8-(Trifluoromethyl)Isoquinolin-3-Ol
CAS No.	1175271-71-2
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	3-Hydroxy-8-(trifluoromethyl)isoquinoline; 8-(Trifluoromethyl)-3-isoquinolinol; 8-Trifluoromethylisoquinolin-3-ol; 1175271-71-2; 3-Isoquinolinol, 8-(trifluoromethyl)-; AI3-71431
EINECS	Contact for details

Quality Control

Every batch of 8-(Trifluoromethyl)Isoquinolin-3-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.