Description

7-(Trifluoromethyl)Isoquinolin-3-Ol is a high-value trifluoromethyl-substituted isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining the isoquinoline scaffold with a metabolically stable trifluoromethyl group, makes it indispensable for creating novel compounds with enhanced properties. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science: Building block for creating specialty chemicals, ligands for catalysis, and organic electronic materials.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Fluorine Chemistry: A valuable compound for studying the introduction and effects of fluorine atoms in complex heterocyclic systems.

Basic Information

Product Name	7-(Trifluoromethyl)Isoquinolin-3-Ol
CAS No.	1175271-56-3
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	3-Hydroxy-7-(trifluoromethyl)isoquinoline; 7-(Trifluoromethyl)-3-isoquinolinol; 7-Trifluoromethylisoquinolin-3-ol; 3-Isoquinolinol, 7-(trifluoromethyl)-; 1175271-56-3; 7-Trifluoromethyl-3-hydroxyisoquinoline
EINECS	Contact for details

Quality Control

Our production of 7-(Trifluoromethyl)Isoquinolin-3-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.