Description

6-(Trifluoromethyl)Isoquinolin-3-Ol is a specialized fluorinated isoquinoline derivative, a high-value building block in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold and the electron-withdrawing trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, oncology, and anti-infective therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Acts as a building block for advanced organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to create fluorescent tags or molecular probes for studying enzyme mechanisms and protein interactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	6-(Trifluoromethyl)Isoquinolin-3-Ol
CAS No.	1175271-49-4
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	3-Hydroxy-6-(trifluoromethyl)isoquinoline; 6-(Trifluoromethyl)-3-isoquinolinol; 6-Trifluoromethylisoquinolin-3-ol; 3-Isoquinolinol, 6-(trifluoromethyl)-; 1175271-49-4; 6-Trifluoromethyl-3-hydroxyisoquinoline
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Isoquinolin-3-Ol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under GMP-like controls for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.