Description

1-(1-Ethyl-1H-Pyrazol-4-Yl)-2,2,2-Trifluoroethanone is a high-value trifluoromethyl ketone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the efficient introduction of the 1-ethylpyrazole moiety and the reactive trifluoroacetyl group into complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

This specialized building block is utilized in several high-tech synthesis pathways, including:

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the pyrazole and trifluoromethyl groups for bioactivity.
• Material Science Chemistry: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Ligand Synthesis: Employed in the creation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable reagent for investigating structure-activity relationships (SAR) in fluorinated compounds.

Basic Information

Product Name	1-(1-Ethyl-1H-Pyrazol-4-Yl)-2,2,2-Trifluoroethanone
CAS No.	1174848-25-9
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	1-(1-Ethyl-1H-pyrazol-4-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1-ethyl-1H-pyrazol-4-yl)ethanone; 1-(1-Ethyl-1H-pyrazol-4-yl)-2,2,2-trifluoroethan-1-one; 1-Ethyl-4-(trifluoroacetyl)-1H-pyrazole; 4-Trifluoroacetyl-1-ethylpyrazole; TFAP-Et; Ethyl-pyrazole-trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our production of 1-(1-Ethyl-1H-Pyrazol-4-Yl)-2,2,2-Trifluoroethanone adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.