Description

1-(1,3-Dimethylpyrazol-4-Yl)-2,2-Difluoro-Ethanone is a high-purity fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique difluoroacetyl moiety attached to a dimethylpyrazole ring, enabling precise molecular modifications that are essential for developing novel compounds. This intermediate is particularly sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the introduction of fluorine atoms can improve metabolic stability and bioactivity.
• Material Science Research: Acts as a precursor for specialty polymers or liquid crystals that require fluorinated heterocyclic components for specific electronic or surface properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and fine chemical production under cGMP or ISO standards.

Basic Information

Product Name	1-(1,3-Dimethylpyrazol-4-Yl)-2,2-Difluoro-Ethanone
CAS No.	1174846-40-2
Molecular Formula	C7H8F2N2O
Molecular Weight	174.15 g/mol
Synonyms	2,2-Difluoro-1-(1,3-dimethyl-1H-pyrazol-4-yl)ethanone; 1-(1,3-Dimethyl-1H-pyrazol-4-yl)-2,2-difluoroethanone; 4-Acetyl-1,3-dimethylpyrazole, 2,2-difluoro-; 1,3-Dimethyl-4-(2,2-difluoroacetyl)pyrazole; 1174846-40-2; Difluoro(1,3-dimethyl-1H-pyrazol-4-yl)methanone
EINECS	Contact for details

Quality Control

Our 1-(1,3-Dimethylpyrazol-4-Yl)-2,2-Difluoro-Ethanone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent batch-to-batch reliability. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.