Description

Rac-n-Benzyl-3-(4-Methoxyphenyl)-2-Propylamine-D6 is a deuterium-labeled isotopologue of a benzylamine derivative, serving as a critical internal standard and tracer in advanced analytical chemistry. This compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical research organizations, contract research laboratories, and academic institutions engaged in drug development and bioanalytical method validation.

Application

• Internal Standard for LC-MS/MS: Used as a stable, non-interfering reference compound for the precise quantification of its non-deuterated counterpart in complex biological matrices like plasma, serum, and tissue homogenates.
• Drug Metabolism and Pharmacokinetics (DMPK): Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical research.
• Bioanalytical Method Development: Critical for validating robust, sensitive, and specific analytical methods in compliance with FDA and ICH guidelines.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision analytical techniques to achieve superior accuracy by correcting for sample preparation and instrument variability.
• Metabolite Identification: Aids in distinguishing drug-derived metabolites from endogenous compounds in mass spectrometry-based studies.
• Pharmaceutical Impurity Profiling: Assists in the identification and quantification of process-related impurities and degradation products during API development.

Basic Information

Item	Details
Product Name	Rac-n-Benzyl-3-(4-Methoxyphenyl)-2-Propylamine-D6
CAS No.	1174538-53-4
Molecular Formula	C17H15D6NO
Molecular Weight	249.39 g/mol
Synonyms	rac-1-(Benzyl-D6)-3-(4-methoxyphenyl)propan-2-amine; (±)-N-Benzyl-3-(4-methoxyphenyl)-2-propylamine-D6; 1-(Benzyl-D6)-3-(4-methoxyphenyl)-2-propylamine; 2-Amino-1-(4-methoxyphenyl)-3-(phenylmethyl-D6)propane; N-Benzyl-D6-3-(4-methoxyphenyl)-2-propylamine; 3-(4-Methoxyphenyl)-2-[(phenylmethyl-D6)amino]propane; Deuterated Benzylamine Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Rac-n-Benzyl-3-(4-Methoxyphenyl)-2-Propylamine-D6 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (D-content), and identification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which could affect stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity (Titration/Non-Volatile Matter)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.