Description

Methyl 5-(tert-Butoxycarbonyl(Methyl)Amino)Thiophene-2-Carboxylate is a high-purity, protected amino acid derivative featuring a thiophene heterocycle, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, particularly those targeting neurological disorders, inflammation, and oncology.
• Peptidomimetic Research: Used to incorporate thiophene-based, N-Boc protected amino acid motifs into peptide analogs to enhance stability and bioavailability.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, and insecticides with heterocyclic cores.
• Material Science: Employed in the synthesis of organic semiconductors, conductive polymers, and liquid crystals due to the electron-rich thiophene unit.
• Chemical Biology Probes: Utilized in the design and synthesis of labeled compounds and molecular probes for biochemical assays.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific, protected heterocyclic carboxylic acid derivatives.

Basic Information

Product Name	Methyl 5-(tert-Butoxycarbonyl(Methyl)Amino)Thiophene-2-Carboxylate
CAS No.	1174316-17-6
Molecular Formula	C12H17NO4S
Molecular Weight	271.33 g/mol
Synonyms	Methyl 5-[(tert-butoxycarbonyl)(methyl)amino]thiophene-2-carboxylate; 5-[(tert-Butoxycarbonyl)(methyl)amino]thiophene-2-carboxylic acid methyl ester; Methyl 5-((tert-butoxycarbonyl)(methyl)amino)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-[(1,1-dimethylethoxy)carbonyl](methyl)amino]-, methyl ester; Boc-N(Me)-2-Thiophene-COOMe; N-Boc-N-Methyl-5-amino-2-thiophenecarboxylic acid methyl ester; N-Methyl-N-(tert-butoxycarbonyl)-5-amino-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(tert-Butoxycarbonyl(Methyl)Amino)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.