Description

Ethyl 8-Chloro-2,3,4,9-Tetrahydro-1H-Carbazole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the carbazole class of heterocyclic compounds. This molecule is of significant commercial interest due to its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules for therapeutic applications, particularly in central nervous system (CNS) and oncology research. The compound, identified by CAS NO 1173908-52-5, is supplied under stringent quality control to ensure batch-to-batch consistency for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those with carbazole-based scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Integral to the development and process chemistry for potential Active Pharmaceutical Ingredients targeting neurological disorders.
• Organic Synthesis: Employed in academic and industrial laboratories for the construction of complex heterocyclic systems and fine chemicals.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	Ethyl 8-Chloro-2,3,4,9-Tetrahydro-1H-Carbazole-3-Carboxylate
CAS No.	1173908-52-5
Molecular Formula	C15H16ClNO2
Molecular Weight	277.75 g/mol
Synonyms	Ethyl 8-chloro-1,2,3,4-tetrahydro-9H-carbazole-3-carboxylate; 8-Chloro-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid ethyl ester; 1H-Carbazole-3-carboxylic acid, 8-chloro-2,3,4,9-tetrahydro-, ethyl ester; 8-Chloro-1,2,3,4-tetrahydrocarbazole-3-carboxylic Acid Ethyl Ester; 1173908-52-5; Carbazole derivative intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 8-Chloro-2,3,4,9-Tetrahydro-1H-Carbazole-3-Carboxylate is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support development with specifications aligned with ICH guidelines for impurities and stability. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.