Description

4-(Aminomethyl)-5-(Hydroxymethyl)-2-(Trideuteriomethyl)Pyridin-3-Ol CAS NO 1173148-03-2 is a deuterated pyridine derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate or building block in the synthesis of deuterated drug molecules, which can offer improved metabolic stability and pharmacokinetic profiles. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas requiring isotopic labeling for metabolic studies or drug optimization.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs).
• Metabolic Tracer: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and analyze metabolic pathways.
• Isotope Labeling Reagent: Serves as a source of deuterium for the preparation of isotopically labeled compounds for research.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new drug candidates with enhanced properties.
• Reference Standard: Can be used as an analytical standard for quality control and method development in analytical laboratories.
• Biochemical Probe Development: Useful in creating probes for studying enzyme mechanisms or biological processes.

Basic Information

Product Name	4-(Aminomethyl)-5-(Hydroxymethyl)-2-(Trideuteriomethyl)Pyridin-3-Ol
CAS No.	1173148-03-2
Molecular Formula	C8H11D3N2O2
Molecular Weight	173.22 g/mol (for C8H11D3N2O2)
Synonyms	2-(Trideuteriomethyl)-4-(aminomethyl)-5-(hydroxymethyl)pyridin-3-ol; 3-Pyridinol, 4-(aminomethyl)-5-(hydroxymethyl)-2-(trideuteriomethyl)-; Deuterated Pyridoxamine Derivative; 4-(Aminomethyl)-5-(hydroxymethyl)-2-(2H3methyl)pyridin-3-ol; 2-(Methyl-d3)-4-(aminomethyl)-5-(hydroxymethyl)-3-pyridinol
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-5-(Hydroxymethyl)-2-(Trideuteriomethyl)Pyridin-3-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, isotopic enrichment, and consistency. Certificates of Analysis (COA) are provided, detailing specifications such as assay (HPLC), deuterium enrichment (NMR/MS), and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.