Description

Pyridoxal-D3 Hydrochloride is a high-purity, deuterium-labeled isotopologue of pyridoxal hydrochloride, a key form of vitamin B6. This stable-labeled compound is essential for advanced analytical and research applications where precise metabolic tracing and quantification are required. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and manufacturers of diagnostic reagents and reference standards.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical quantitative standard in mass spectrometry for the accurate measurement of vitamin B6 vitamers in complex biological matrices.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of vitamin B6 and related compounds.
• Diagnostic Reagent Manufacturing: A key raw material in the production of high-sensitivity clinical assay kits for nutritional status assessment and metabolic disorder diagnostics.
• Pharmaceutical Reference Standard: Employed as a certified reference material (CRM) for method development, validation, and quality control in pharmaceutical analysis.
• Nutritional Research: Facilitates advanced studies on vitamin B6 bioavailability, turnover, and its role in human health and disease.
• Isotope Dilution Mass Spectrometry (IDMS): Provides the definitive method for achieving high accuracy and precision in the quantification of pyridoxal and its metabolites.

Basic Information

Product Name	Pyridoxal-D3 Hydrochloride
CAS No.	1173023-49-8
Molecular Formula	C8H6D3ClNO3
Molecular Weight	215.65 g/mol
Synonyms	Pyridoxal-d3 HCl; 4-Formyl-3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-d3 hydrochloride; Vitamin B6 aldehyde-d3 hydrochloride; 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde-d3 hydrochloride; Deuterated Pyridoxal Hydrochloride; [2H3]-Pyridoxal Hydrochloride; (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methanol-d3 hydrochloride
EINECS	Contact for details

Quality Control

Our Pyridoxal-D3 Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including NMR and mass spectrometry for isotopic enrichment verification and HPLC for chemical purity, to ensure it meets the exacting standards required for analytical and research applications. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Isotopic Enrichment	≥ 99.0% (D3)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.