Description

7-Fluoro-5-Iodoindole is a high-purity, multi-functional halogenated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an invaluable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitors, receptor modulators, and CNS-active compounds.
• Agrochemical Research: Used in the synthesis of new-generation herbicides, fungicides, and plant growth regulators that require halogenated heterocyclic cores.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of organic semiconductors, OLED materials, and conductive polymers.
• Chemical Biology & Proteomics: Employed as a labeling reagent or a scaffold for designing molecular probes and activity-based protein profiling (ABPP) agents.
• Cross-Coupling Reactions: The iodine atom provides an excellent handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck).
• Fluorine Chemistry Exploration: Used to study the effects of fluorine substitution on the reactivity and physicochemical properties of indole-based systems.

Basic Information

Product Name	7-Fluoro-5-Iodoindole
CAS No.	1173023-15-8
Molecular Formula	C8H5FIN
Molecular Weight	261.04 g/mol
Synonyms	5-Iodo-7-fluoroindole; 7-Fluoro-5-iodo-1H-indole; 1H-Indole, 7-fluoro-5-iodo-; 5-Iodo-7-fluoro-1H-indole; 7-Fluoro-5-iodoindole; F5II
EINECS	Contact for details

Quality Control

Our 7-Fluoro-5-Iodoindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.